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. 2017 Apr;40(2):119-129.
Epub 2017 Apr 3.

Antimicrobial consumption and antimicrobial resistance: a snapshot of an Italian neuromuscular rehabilitation center

Giuseppina Barberi  1 , Maria Cristina De Cola  1 , De Cola Dell'Utri  1 , Sara Melardi  1 , Bernardo Alagna  1 , Placido Bramanti  1 , Antonio Cascio  2
Affiliations
  • PMID: 28368076
Free article

Antimicrobial consumption and antimicrobial resistance: a snapshot of an Italian neuromuscular rehabilitation center

Giuseppina Barberi et al. New Microbiol. 2017 Apr.
Free article

Abstract

The paper presents a snapshot of the incidence of antimicrobial-resistant microorganisms and antimicrobial consumption in an Italian rehabilitation center over a two-year period (2014-2015). Data on microorganism identification and antimicrobial susceptibility testing were obtained from the diagnostic laboratory of the hospital. A set of indicators was assessed, including the incidence density of resistant isolates per 1000 patient-days (IDRI). Data on antimicrobial consumption, semi-annually, obtained from the hospital pharmacy, were expressed as Defined Daily Dose (DDD) per 1000 patient-days. The most frequently isolated microorganism was Klebsiella pneumoniae (19.3%), and a significant increase in piperacillin/tazobactam- resistant K. pneumoniae (p=0.04) was observed. Among all antimicrobials used, carbapenems were the most prescribed antibiotic class (31%).

Keywords: Antimicrobial consumption; Antimicrobial resistance; DDD per 1000 patient-days; Healthcare-associated infections; Rehabilitation hospital.

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