Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1988 May 11;16(9):4121-36.
doi: 10.1093/nar/16.9.4121.

Histone genes of Volvox carteri: DNA sequence and organization of two H3-H4 gene loci

K Müller  1 , R Schmitt
Affiliations
Free PMC article

Histone genes of Volvox carteri: DNA sequence and organization of two H3-H4 gene loci

K Müller et al. Nucleic Acids Res. .
Free PMC article

Erratum in

  • Nucleic Acids Res 1988 Jun 24;16(12):5712

Abstract

Two Volvox genomic clones each containing a pair of histone H3-H4 genes were sequenced. In both loci the H3 and H4 genes show outwardly divergent polarity, their coding regions being separated by short intercistronic sequences containing TATA boxes and a conserved 14-bp element. The 3' untranslated regions contain a characteristic motif with hyphenated dyad symmetry otherwise only found associated with animal histone genes. Derived amino acid sequences of histones H3 and H4 are highly conserved and identical between the two sets. The Volvox H3 genes both contain one intron whose relative position is shifted by one basepair. Sequence comparisons led to a new interpretation of intron sliding. The Volvox H3 gene structure combines the exon-intron organization of fungal H3 and vertebrate H3.3 genes with a termination signal typical for animal H3.1 genes. These features are discussed in view of histone gene evolution.

PubMed Disclaimer

References

    1. Nucleic Acids Res. 1982 Jun 25;10(12):3769-80 - PubMed
    1. Nucleic Acids Res. 1986;14 Suppl:r119-49 - PubMed
    1. Gene. 1986;42(2):225-9 - PubMed
    1. Nucleic Acids Res. 1988 Feb 25;16(4):1295-304 - PubMed
    1. Nucleic Acids Res. 1986 Dec 22;14(24):10009-26 - PubMed

Publication types

Associated data