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. 2017 Jun 15;64(12):1644-1656.
doi: 10.1093/cid/cix212.

The Human Immunodeficiency Virus Continuum of Care in European Union Countries in 2013: Data and Challenges

Affiliations

The Human Immunodeficiency Virus Continuum of Care in European Union Countries in 2013: Data and Challenges

Annabelle Gourlay et al. Clin Infect Dis. .

Abstract

Background.: The Joint United Nations Programme on HIV/AIDS (UNAIDS) has set a "90-90-90" target to curb the human immunodeficiency virus (HIV) epidemic by 2020, but methods used to assess whether countries have reached this target are not standardized, hindering comparisons.

Methods.: Through a collaboration formed by the European Centre for Disease Prevention and Control (ECDC) with European HIV cohorts and surveillance agencies, we constructed a standardized, 4-stage continuum of HIV care for 11 European Union countries for 2013. Stages were defined as (1) number of people living with HIV in the country by end of 2013; (2) proportion of stage 1 ever diagnosed; (3) proportion of stage 2 that ever initiated ART; and (4) proportion of stage 3 who became virally suppressed (≤200 copies/mL). Case surveillance data were used primarily to derive stages 1 (using back-calculation models) and 2, and cohort data for stages 3 and 4.

Results.: In 2013, 674500 people in the 11 countries were estimated to be living with HIV, ranging from 5500 to 153400 in each country. Overall HIV prevalence was 0.22% (range, 0.09%-0.36%). Overall proportions of each previous stage were 84% diagnosed, 84% on ART, and 85% virally suppressed (60% of people living with HIV). Two countries achieved ≥90% for all stages, and more than half had reached ≥90% for at least 1 stage.

Conclusions.: European Union countries are nearing the 90-90-90 target. Reducing the proportion undiagnosed remains the greatest barrier to achieving this target, suggesting that further efforts are needed to improve HIV testing rates. Standardizing methods to derive comparable continuums of care remains a challenge.

Keywords: HIV infection; antiretroviral therapy.; cohort analysis; continuum of care; surveillance.

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Figures

Figure 1.
Figure 1.
Continuum of human immunodeficiency virus (HIV) care in 11 European Union countries (Austria, Belgium, Denmark, France, Germany, Greece, Italy, The Netherlands, Spain, Sweden, and United Kingdom) for 2013. Weighted averages, accounting for the number of HIV-infected individuals at each stage in each country, were taken across all countries for each stage.*Percentages out of the previous stage. **Percentages among all people living with HIV by the end of 2013. Abbreviations: ART, antiretroviral therapy; PLHIV, people living with human immunodeficiency virus; VL, viral load.

References

    1. Centers for Disease Control and Prevention. Vital signs: HIV prevention through care and treatment—United States. MMWR Morb Mortal Wkly Rep 2011; 60:1618–23. - PubMed
    1. Joint United Nations Programme on HIV/AIDS. 90-90-90 an ambitious target to help end the AIDS epidemic. Geneva, Switzerland: UNAIDS, 2014.
    1. European Centre for Disease Prevention and Control. Thematic report: HIV continuum of care. Monitoring implementation of the Dublin Declaration on Partnership to Fight HIV/AIDS in Europe and Central Asia: 2014 progress report. Stockholm, Sweden: ECDC, 2015.
    1. Drew RS, Rice B, Ruutel K, et al. HIV continuum of care in Europe and Central Asia [Epub ahead of print]. HIV Med 2017. doi:10.1111/hiv.12480. - PMC - PubMed
    1. Medland NA, McMahon JH, Chow EP, Elliott JH, Hoy JF, Fairley CK. The HIV care cascade: a systematic review of data sources, methodology and comparability. J Int AIDS Soc 2015; 18:20634. - PMC - PubMed

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