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Comment
. 2017 Apr;7(4):354-355.
doi: 10.1158/2159-8290.CD-17-0192.

Exploring the Link between the Germline and Somatic Genome in Cancer

Paul Geeleher  1 , R Stephanie Huang  2
Affiliations
Comment

Exploring the Link between the Germline and Somatic Genome in Cancer

Paul Geeleher et al. Cancer Discov. 2017 Apr.

Abstract

<b/> Carter and colleagues propose a systematic analysis of the germline and somatic genome in cancer. They identify interactions that occur between germline and somatic variants. This elucidates the function of the germline genome in the context of cancer risk and development. Cancer Discov; 7(4); 354-5. ©2017 AACRSee related article by Carter et al., p. 410.

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Conflict of interest statement

Conflict of interest

The authors disclose no potential conflicts of interest.

Comment on

  • Interaction Landscape of Inherited Polymorphisms with Somatic Events in Cancer.
    Carter H, Marty R, Hofree M, Gross AM, Jensen J, Fisch KM, Wu X, DeBoever C, Van Nostrand EL, Song Y, Wheeler E, Kreisberg JF, Lippman SM, Yeo GW, Gutkind JS, Ideker T. Carter H, et al. Cancer Discov. 2017 Apr;7(4):410-423. doi: 10.1158/2159-8290.CD-16-1045. Epub 2017 Feb 10. Cancer Discov. 2017. PMID: 28188128 Free PMC article.

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