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Review
. 2017 Apr 1;56(suppl_1):i24-i31.
doi: 10.1093/rheumatology/kew447.

Paediatric systemic lupus erythematosus: insights from translational research

Tracey B Wright  1   2   3 , Marilynn Punaro  1   2   3
Affiliations
Review

Paediatric systemic lupus erythematosus: insights from translational research

Tracey B Wright et al. Rheumatology (Oxford). .

Abstract

Investigations in paediatric SLE contributed significantly to the discovery of the association of type I IFNs with lupus and underscored the potential application of this knowledge by informing the use of glucocorticoid therapy. Recent, promising research reveals biomarkers that may yield more focused clinical monitoring and assessment of response to treatment. This article reviews unique features of paediatric SLE and details important developments in paediatric lupus research.

Keywords: biomarker; microarray; paediatric; systemic lupus erythematosus.

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