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Comparative Study
. 2017 Aug;104(9):1244-1249.
doi: 10.1002/bjs.10527. Epub 2017 Apr 4.

Evaluation of the peritoneal carcinomatosis index with CT and MRI

A Dohan  1   2 , C Hoeffel  3 , P Soyer  1 , A S Jannot  4 , P-J Valette  5 , A Thivolet  5 , G Passot  6 , O Glehen  6 , P Rousset  5
Affiliations
Comparative Study

Evaluation of the peritoneal carcinomatosis index with CT and MRI

A Dohan et al. Br J Surg. 2017 Aug.

Abstract

Background: The aim was to determine the incremental value of MRI compared with CT in the preoperative estimation of the peritoneal carcinomatosis index (PCI).

Methods: CT and MRI examinations of patients with peritoneal carcinomatosis were evaluated. CT images were first analysed by two observers who determined a first PCI (PCICT ). Then, the two observers reviewed MRI examinations in combination with CT and determined a second PCI (PCICT+MRI ). The sensitivity and negative predictive value of the two imaging sets were determined using surgery as a reference standard (PCIRef ).

Results: CT plus MRI was more accurate in predicting the surgical PCI than CT alone. The absolute difference between PCICT+MRI and PCIRef was lower than that between PCICT and PCIRef (mean(s.d.) 3·96(4·10) versus 4·89(4·73); P = 0·010). The number of true-positive findings increased from 106 to 125 for reader 1 and from 117 to 132 for reader 2 with the adjunct of MRI. For both readers, an increased sensitivity was obtained when both MRI and CT were used (from 63 to 81 per cent for reader 1; from 44 to 81 per cent for reader 2). The increase in sensitivity was greater for patients with a moderate volume of disease.

Conclusion: The combination of CT and MRI improved the preoperative estimation of PCI compared with CT alone.

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