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Comment
. 2017 Apr 4;25(4):759-760.
doi: 10.1016/j.cmet.2017.03.012.

Brown Fat-Derived Exosomes: Small Vesicles with Big Impact

Yong Chen  1 , Alexander Pfeifer  2
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Brown Fat-Derived Exosomes: Small Vesicles with Big Impact

Yong Chen et al. Cell Metab. .
Free article

Abstract

Adipose tissue (AT) not only stores energy, but also secretes hormones and releases small vesicles known as exosomes. Thomou et al. (2017) now show that exosomes secreted by brown fat carry miRNAs that regulate the liver. Thus, AT exosomes might have therapeutic and diagnostic relevance for metabolic disorders.

Keywords: FGF21; biomarker; brown adipose tissue; exosomes; liver; microRNAs; white adipose tissue.

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