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Comment
. 2017 Apr 4;25(4):761-762.
doi: 10.1016/j.cmet.2017.03.013.

Now UCP(rotein), Now You Don't: UCP1 Is Not Mandatory for Thermogenesis

Ildiko Szabo  1 , Mario Zoratti  2
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Now UCP(rotein), Now You Don't: UCP1 Is Not Mandatory for Thermogenesis

Ildiko Szabo et al. Cell Metab. .
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Abstract

Adipocyte-targeted therapies could potentially combat obesity and metabolic disorders; however, our understanding of adipogenesis and the characterization of the various adipose tissues are incomplete. In this issue, Bertholet et al. (2017) report the existence of two types of heat-producing beige-like adipocytes, those with and those without the mitochondrial uncoupling protein 1 (UCP1).

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