Clocks stop sugar shock

Affiliations

Comment

Jeffrey Haspel. Sci Transl Med. 2017.

. 2017 Apr 5;9(384):eaan2772.

doi: 10.1126/scitranslmed.aan2772.

¹ Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, St. Louis, MO 63130, USA. Email: jhaspel@dom.wustl.edu.

Abstract

The circadian clock orchestrates the timing of insulin and glucagon secretion, which is important for glycemic control.

Pancreatic α- and β-cellular clocks have distinct molecular properties and impact on islet hormone secretion and gene expression.
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