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. 2017 Aug;36(8):808-810.
doi: 10.1097/INF.0000000000001596.

Clinical Profiles of Respiratory Syncytial Virus Subtypes A AND B Among Children Hospitalized with Bronchiolitis

Federico R Laham  1 , Jonathan M Mansbach, Pedro A Piedra, Kohei Hasegawa, Ashley F Sullivan, Janice A Espinola, Carlos A Camargo Jr
Affiliations

Clinical Profiles of Respiratory Syncytial Virus Subtypes A AND B Among Children Hospitalized with Bronchiolitis

Federico R Laham et al. Pediatr Infect Dis J. 2017 Aug.

Abstract

In this analysis of a prospective, multicenter study of children hospitalized with bronchiolitis, 925 had respiratory syncytial virus (RSV)-A and 649 had RSV-B. Overall, bronchiolitis severity did not differ by RSV subtype. However, among children with RSV-only bronchiolitis, those children with RSV-A had higher risk of intensive care treatment (odds ratio, 1.31; 95% confidence interval, 1.00-1.71; P = 0.048) when compared with those having RSV-B.

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Conflict of interest statement

Conflict of Interest: P.A.P. and J.M.M. were consultants for Regeneron Pharmaceuticals, Inc. All other authors did not have conflict of interests.

References

    1. Hasegawa K, Mansbach JM, Camargo CA., Jr Infectious pathogens and bronchiolitis outcomes. Expert Rev Anti Infect Ther. 2014;12:817–828. - PubMed
    1. Walsh EE, McConnochie KM, Long CE, Hall CB. Severity of respiratory syncytial virus infection is related to virus strain. J Infect Dis. 1997;175:814–820. - PubMed
    1. McConnochie KM, Hall CB, Walsh EE, Roghmann KJ. Variation in severity of respiratory syncytial virus infections with subtype. J Pediatr. 1990;117:52–62. - PubMed
    1. Papadopoulos NG, Gourgiotis D, Javadyan A, et al. Does respiratory syncytial virus subtype influences the severity of acute bronchiolitis in hospitalized infants? Respir Med. 2004;98:879–882. - PubMed
    1. Hornsleth A, Klug B, Nir M, et al. Severity of respiratory syncytial virus disease related to type and genotype of virus and to cytokine values in nasopharyngeal secretions. Pediatr Infect Dis J. 1998;17:1114–1121. - PubMed

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