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Review
. 2017;10(2):112-117.
doi: 10.1159/000456668. Epub 2017 Apr 7.

Effect of Maternal Obesity on Foetal Growth and Metabolic Health of the Offspring

Affiliations
Review

Effect of Maternal Obesity on Foetal Growth and Metabolic Health of the Offspring

Claudio Maffeis et al. Obes Facts. 2017.

Abstract

Maternal and placental conditions that are unfavourable for the embryo/foetus have long-lasting effects on different tissues and functions of the body, which may persist for life and, potentially, also be transmitted to the offspring. This review resumes current evidence on principle maternal and gestational conditions associated with unfavourable metabolic programming of the offspring, along with their mechanisms of action, either supposed or already proved.

Keywords: Foetal growth; Maternal obesity; Metabolic health.

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References

    1. Maffeis C, Micciolo R, Must A, Zaffanello M, Pinelli L. Parental and perinatal factors associated with childhood obesity in north-east Italy. Int J Obes Relat Metab Disord. 1994;18:301–305. - PubMed
    1. Whitaker RC, Wright JA, Pepe MS, Seidel KD, Dietz WH. Predicting obesity in young adulthood from childhood and parental obesity. N Engl J Med. 1997;337:869–873. - PubMed
    1. Stunkard AJ, Foch TT, Hrubec Z. A twin study of human obesity. JAMA. 1986;256:51–54. - PubMed
    1. Silventoinen K, Rokholm B, Kaprio J, Sørensen TI. The genetic and environmental influences on childhood obesity: a systematic review of twin and adoption studies. Int J Obes (Lond) 2010;34:29–40. - PubMed
    1. Morandi A, Meyre D, Lobbens S, Kleinman K, Kaakinen M, Rifas-Shiman SL, Vatin V, Gaget S, Pouta A, Hartikainen AL, Laitinen J, Ruokonen A, Das S, Khan AA, Elliott P, Maffeis C, Gillman MW, Järvelin MR, Froguel P. Estimation of newborn risk for child or adolescent obesity: lessons from longitudinal birth cohorts. PLoS One. 2012;7:e49919. - PMC - PubMed