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Comparative Study
. 1988 Jun:69 ( Pt 6):1383-9.
doi: 10.1099/0022-1317-69-6-1383.

The complete nucleotide sequence of the genome of a hepatitis B virus isolated from a naturally infected chimpanzee

M Vaudin  1 , A J Wolstenholme, K N Tsiquaye, A J Zuckerman, T J Harrison
Affiliations
Comparative Study

The complete nucleotide sequence of the genome of a hepatitis B virus isolated from a naturally infected chimpanzee

M Vaudin et al. J Gen Virol. 1988 Jun.

Abstract

The complete nucleotide sequence of a strain of hepatitis B virus, originally isolated from a naturally infected chimpanzee, has been determined. Interesting features of the sequence include the presence of an in-phase stop codon in the 'pre-core' region of the core antigen open reading frame. The sequence shows approximately 10% nucleotide divergence from all of the other hepatitis B virus sequences previously published and the possibility that this divergence is the result of passage through chimpanzees is discussed.

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