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. 1988 Jun:69 ( Pt 6):1411-4.
doi: 10.1099/0022-1317-69-6-1411.

Protection of mice from lethal infection with Aujeszky's disease virus by immunization with purified gVI

H Ishii  1 , Y Kobayashi, M Kuroki, Y Kodama
Affiliations

Protection of mice from lethal infection with Aujeszky's disease virus by immunization with purified gVI

H Ishii et al. J Gen Virol. 1988 Jun.

Abstract

Virus envelope glycoprotein gVI (gp50) of Aujeszky's disease virus (ADV) was purified from a Nonidet P40-solubilized lysate of ADV-infected Vero cells by immunoaffinity chromatography using a monoclonal antibody against gVI. Mice immunized by the purified gVI produced virus-neutralizing antibody and were successfully protected against subsequent challenge with ADV.

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