Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2017;55(1):29-37.
doi: 10.5114/reum.2017.66685. Epub 2017 Mar 22.

An ever-challenging relationship: lupus and pregnancy

Affiliations
Review

An ever-challenging relationship: lupus and pregnancy

Andra Bălănescu et al. Reumatologia. 2017.

Abstract

Systemic lupus erythematous (SLE) is a chronic inflammatory disease with an unknown etiology and an autoimmune pathogenesis, and its clinical manifestations can involve multiple organs through polymorphic biological changes. Nowadays, pregnancy is possible for most patients with SLE, and good outcomes can be expected for both mother and child. This became possible as a consequence of increasingly better monitoring and treatment of pregnant women with SLE. The following article outlines the problems associated with fertility, course of pregnancy, and breastfeeding in women with SLE.

Keywords: pregnancy; systemic lupus erythematosus.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

References

    1. Bălănescu A, Parvu M. Ginecologie, ed. Tratat de Chirurgie, Obstetrică si Ginecologie. Bucuresti: Academiei Române; 2014. Lupusul eritematos şi sarcina; pp. 789–801.
    1. Andreoli L, Bertsias KG, Agmon-Levin N, et al. EULAR recommendations for women’s health and the management of family planning, assisted reproduction, pregnancy and menopause in patients with systemic lupus erythematosus and/or antiphospholipid syndrome. Ann Rheum Dis. 2017;76:476–485. - PMC - PubMed
    1. Østensen M, Andreoli L, Brucatoc A, et al. State of the art: Reproduction and pregnancy in rheumatic diseses. Autoimmun Rev. 2015;14:376–386. - PubMed
    1. Ruiz-Irastorza G, Khamashta MA. Lupus and pregnancy: integrating clues from the bench and bedside. Eur J Clin Invest. 2011;41:672–678. - PubMed
    1. Clowse MEB, Chakravarty E, Costenbader KH, et al. The effects of infertility, pregnancy loss, and patient concerns on family size ofwomenwith rheumatoid arthritis and systemic lupus erythematosus. Arthritis Care Res (Hoboken) 2012;64:668–674. - PubMed

LinkOut - more resources