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. 2017:2017:6878263.
doi: 10.1155/2017/6878263. Epub 2017 Mar 12.

Prevalence and Complications of Pregestational and Gestational Diabetes in Saudi Women: Analysis from Riyadh Mother and Baby Cohort Study (RAHMA)

Hayfaa Wahabi  1 , Amel Fayed  2 , Samia Esmaeil  3 , Heba Mamdouh  4 , Reham Kotb  5
Affiliations

Prevalence and Complications of Pregestational and Gestational Diabetes in Saudi Women: Analysis from Riyadh Mother and Baby Cohort Study (RAHMA)

Hayfaa Wahabi et al. Biomed Res Int. 2017.

Abstract

The objectives of this study were to estimate the burden of diabetes and to explore the adverse pregnancy outcomes associated with pregestational diabetes mellitus (pre-GDM) and gestational diabetes mellitus (GDM) among the Saudi pregnant population. In this subcohort, we compared the maternal and the neonatal outcomes of diabetic women with pre-GDM and GDM to the outcomes of nondiabetic mothers who delivered during the same period. From the total cohort, 9723 women participated in this study. Of the participants, 24.2% had GDM, 4.3% had pre-GDM, and 6951 were nondiabetic. After adjustment for confounders, women with GDM had increased odds of delivering a macrosomic baby (OR: 1.6; 95% CI: 1.2-2.1). Women with pre-GDM were more likely to deliver by Cesarean section (OR: 1.65; CI: 1.32-2.07) and to have preterm delivery < 37 weeks (OR: 2.1; CI: 1.5-2.8). Neonates of mothers with pre-GDM were at increased risk of being stillbirth (OR: 3.66; CI: 1.98-6.72), at increased risk of admission to NICU (OR: 2.21; CI: 1.5-3.27), and at increased risk for being macrosomic (OR: 2.40; CI: 1.50-3.8). The prevalence of GDM and pre-GDM in the Saudi pregnant population is among the highest in the world. The conditions are associated with high maternal and neonatal morbidities and mortalities.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Figure 1
Figure 1
Prevalence of gestational and pregestational diabetes by age range.
Figure 2
Figure 2
Prevalence of gestational diabetes and pregestational diabetes and body mass index groups.
See this image and copyright information in PMC

References

    1. International Diabetes Federation. IDF Diabetes Atlas. 6th. Brussels, Belgium: International Diabetes Federation; 2013. - PubMed
    1. Majeed A., El-Sayed A. A., Khoja T., Alshamsan R., Millett C., Rawaf S. Diabetes in the Middle-East and North Africa: an update. Diabetes Research and Clinical Practice. 2014;103(2):218–222. doi: 10.1016/j.diabres.2013.11.008. - DOI - PubMed
    1. Wahabi H., Fayed A., Esmaeil S., et al. Riyadh mother and baby multicenter cohort Study: the cohort profile. PLoS ONE. 2016;11(3) doi: 10.1371/journal.pone.0150297.e0150297 - DOI - PMC - PubMed
    1. Zhu Y., Zhang C. Prevalence of gestational diabetes and risk of progression to type 2 diabetes: a global perspective. Current Diabetes Reports. 2016;16(1, article 7) doi: 10.1007/s11892-015-0699-x. - DOI - PMC - PubMed
    1. Guariguata L., Linnenkamp U., Beagley J., Whiting D. R., Cho N. H. Global estimates of the prevalence of hyperglycaemia in pregnancy. Diabetes Research and Clinical Practice. 2014;103(2):176–185. doi: 10.1016/j.diabres.2013.11.003. - DOI - PubMed

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