Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1978 Aug;41(8):709-12.
doi: 10.1136/jnnp.41.8.709.

Evidence for a change in neurotransmitter affecting oesophageal motility in Parkinson's disease

M G Bramble, J Cunliffe, A W Dellipiani

Evidence for a change in neurotransmitter affecting oesophageal motility in Parkinson's disease

M G Bramble et al. J Neurol Neurosurg Psychiatry. 1978 Aug.

Abstract

In a study of oesophageal motility in 20 patients with Parkinson's disease, intravenous atropine produced marked disruption of co-ordination in response to swallows, when compared with control subjects. This suggests that cholinergic rather than dopaminergic mechanisms are more important in the control of swallowing in patients with Parkinsonism. No conclusive evidence of peripheral dopamine depletion or autonomic neuropathy was found, although minor changes suggestive of the former were found in severely affected patients.

PubMed Disclaimer

References

    1. Brain. 1963 Dec;86:781-92 - PubMed
    1. Australas Ann Med. 1965 Feb;14:13-22 - PubMed
    1. Lancet. 1972 Jan 22;1(7743):174-6 - PubMed
    1. J Physiol (Paris). 1972;64(5):479-506 - PubMed
    1. Arch Neurol. 1967 Aug;17(2):124-36 - PubMed

LinkOut - more resources