Integration of PET/MR Hybrid Imaging into Radiation Therapy Treatment

Abstract

Hybrid PET/MR imaging is in early development for treatment planning. This article briefly reviews research and clinical applications of PET/MR imaging in radiation oncology. With improvements in workflow, more specific tracers, and fast and robust acquisition protocols, PET/MR imaging will play an increasingly important role in better target delineation for treatment planning and have clear advantages in the evaluation of tumor response and in a better understanding of tumor heterogeneity. With advances in treatment delivery and the potential of integrating PET/MR imaging with research on radiomics for radiation oncology, quantitative and physiologic information could lead to more precise and personalized RT.

Keywords: Hybrid PET/MR imaging; MRI-based treatment planning; Normal tissue toxicity; PET tracers; Radiation therapy; Tumor heterogeneity; Tumor response.