Pediatric Multiple Sclerosis: Distinguishing Clinical and MR Imaging Features

Abstract

This article presents an overview of evolving diagnostic criteria of pediatric multiple sclerosis and related disorders, emphasizing distinguishing clinical and neuroimaging features that should be considered for differential diagnosis in childhood and adolescence. New data on the integrity of brain tissue in children with MS provided by advanced MR imaging techniques are addressed as well.

Keywords: Acquired demyelinating syndromes; Acute disseminated encephalomyelitis; Children; Diagnostic criteria; MR imaging; Neuromyelitis optica; Pediatric multiple sclerosis.