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Case Reports
. 1979 Jan 25;46(2):173-80.
doi: 10.1007/BF00291919.

A new chromosome anomaly in acute lymphoblastic leukemia (ALL)

Case Reports

A new chromosome anomaly in acute lymphoblastic leukemia (ALL)

H Van den Berghe et al. Hum Genet. .

Abstract

A new chromosome anomaly in acute lymphoblastic leukemia (ALL) is reported. Three, possibly four, patients showed an identical karyotype anomaly, characterized by a (4;11)(q13;q22) reciprocal translocation. This anomaly has not so far been found in lymphoproliferative disorders other than ALL. Two of the patients had congenital leukemia, but the anomaly described appears to be more characteristic of ALL than of congenital leukemia, and may help the clinician in establishing the diagnosis of ALL.

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