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. 2017 Jun;38(6):729-731.
doi: 10.1017/ice.2017.53. Epub 2017 Apr 11.

Analysis of Multidrug-Resistant Organism Susceptibility to Chlorhexidine Under Usual Clinical Care

Jackson S Musuuza  1 , Ajay K Sethi  2 , Tonya J Roberts  1 , Nasia Safdar  1
Affiliations

Analysis of Multidrug-Resistant Organism Susceptibility to Chlorhexidine Under Usual Clinical Care

Jackson S Musuuza et al. Infect Control Hosp Epidemiol. 2017 Jun.

Abstract

Increasing use of daily chlorhexidine gluconate (CHG) bathing can potentially lead to selection for organisms with reduced susceptibility to CHG, limiting the utility of CHG. We examined reduced susceptibility to CHG of fluoroquinolone-resistant gram-negative bacilli and methicillin-resistant Staphylococcus. No evidence suggested reduced susceptibility to CHG. Infect Control Hosp Epidemiol 2017;38:729-731.

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Conflict of interest statement

Potential conflicts of interest: All authors report no conflicts of interest relevant to this article.

References

    1. Zimlichman E, Henderson D, Tamir O, et al. Health care– associated infections: a meta-analysis of costs and financial impact on the us health care system. JAMA Intern Med 2013;173: 2039–2046. - PubMed
    1. Horner C, Mawer D, Wilcox M. Reduced susceptibility to chlorhexidine in staphylococci: is it increasing and does it matter? J Antimicrob Chemother 2012;67:2547–2559. - PubMed
    1. Milstone AM, Passaretti CL, Perl TM. Chlorhexidine: expanding the armamentarium for infection control and prevention. Clin Infect Dis 2008;46:274–281. - PubMed
    1. Climo MW, Yokoe DS, Warren DK, et al. Effect of daily chlorhexidine bathing on hospital-acquired infection. N Engl J Med 2013;368:533–542. - PMC - PubMed
    1. Shuman E, Harpe J, Calfee DP. Survey of hospital practices regarding use of chlorhexidine gluconate bathing for prevention of healthcare-associated infections. Open Forum Infectious Diseases 2014;1:S363–S364.

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