Risk of Clostridium difficile Infection in Hematology-Oncology Patients Colonized With Toxigenic C. difficile
- PMID: 28397624
- PMCID: PMC5531265
- DOI: 10.1017/ice.2017.48
Risk of Clostridium difficile Infection in Hematology-Oncology Patients Colonized With Toxigenic C. difficile
Abstract
The prevalence of colonization with toxigenic Clostridium difficile among patients with hematological malignancies and/or bone marrow transplant at admission to a 566-bed academic medical care center was 9.3%, and 13.3% of colonized patients developed symptomatic disease during hospitalization. This population may benefit from targeted C. difficile infection control interventions. Infect Control Hosp Epidemiol 2017;38:718-720.
References
-
- Cohen SH, Gerding DN, Johnson S, et al. Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the society for healthcare epidemiology of America (SHEA) and the infectious diseases society of America (IDSA) Infect Control Hosp Epidemiol. 2010;31(5):431–455. - PubMed
-
- Warrack S, Duster M, Van Hoof S, Schmitz M, Safdar N. Clostridium difficile in a children’s hospital: assessment of environmental contamination. Am J Infect Control. 2014;42(7):802–804. - PubMed
-
- Jain T, Croswell C, Urday-Cornejo V, et al. Clostridium Difficile Colonization in Hematopoietic Stem Cell Transplant Recipients: A Prospective Study of the Epidemiology and Outcomes Involving Toxigenic and Nontoxigenic Strains. Biol Blood Marrow Transplant. 2016;22(1):157–163. - PubMed
-
- Bruminhent J, Wang ZX, Hu C, et al. Clostridium difficile colonization and disease in patients undergoing hematopoietic stem cell transplantation. Biol Blood Marrow Transplant. 2014;20(9):1329–1334. - PubMed
-
- Zacharioudakis IM, Zervou FN, Pliakos EE, Ziakas PD, Mylonakis E. Colonization with toxinogenic C. difficile upon hospital admission, and risk of infection: a systematic review and meta-analysis. Am J Gastroenterol. 2015;110(3):381–390. quiz 391. - PubMed
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
