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. 1988 Jul 28;334(6180):314-9.
doi: 10.1038/334314a0.

Transcriptional autoregulation of the proto-oncogene fos

P Sassone-Corsi  1 , J C Sisson, I M Verma
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Transcriptional autoregulation of the proto-oncogene fos

P Sassone-Corsi et al. Nature. .

Abstract

Serum-induced transcription of the proto-oncogene fos is under negative feedback regulation mediated by the fos protein. The fos promoter region responsive to repression is also required for serum inducibility and binds a nucleoprotein complex in which the nuclear factor AP-1 is associated with fos protein.

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