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Review
. 2017 Apr 8;9(4):132.
doi: 10.3390/toxins9040132.

Helicobacter pylori Strains and Gastric MALT Lymphoma

Pauline Floch  1 , Francis Mégraud  2 , Philippe Lehours  3
Affiliations
Review

Helicobacter pylori Strains and Gastric MALT Lymphoma

Pauline Floch et al. Toxins (Basel). .

Abstract

This article summarizes the main findings concerning Helicobacter pylori associated with gastric MALT lymphoma (GML). Considered together, GML strains based on their virulence factor profile appear to be less virulent than those associated with peptic ulcers or gastric adenocarcinoma. A particular Lewis antigen profile has been identified in GML strains and could represent an alternative adaptive mechanism to escape the host immune response thereby allowing continuous antigenic stimulation of infiltrating lymphocytes.

Keywords: Helicobacter pylori; MALT lymphoma; cag pathogenicity island; pathogenesis; virulence marker.

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Conflict of interest statement

The authors declare no conflict of interest.

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