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Comment
. 2017 Jun 1;140(6):e35.
doi: 10.1093/brain/awx090.

Serotonergic modulation as a pharmacological modality in the treatment of Dravet syndrome

Peter de Witte  1 , Lieven Lagae  1
Affiliations
Comment

Serotonergic modulation as a pharmacological modality in the treatment of Dravet syndrome

Peter de Witte et al. Brain. .
No abstract available

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References

    1. Baraban SC, Dinday MT, Hortopan GA. Drug screening in Scn1a zebrafish mutant identifies clemizole as a potential Dravet syndrome treatment. Nat Commun 2013; 4: 2410. - PMC - PubMed
    1. Bialer M, Johannessen SI, Levy RH, Perucca E, Tomson T, White HS. Progress report on new antiepileptic drugs: a summary of the Thirteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIII). Epilepsia 2017; 58: 181–221. - PubMed
    1. Ceulemans B, Boel M, Leyssens K, Van Rossem C, Neels P, Jorens PG, Lagae L. Successful use of fenfluramine as an add-on treatment for Dravet syndrome. Epilepsia 2012; 53: 1131–9. - PubMed
    1. Dinday MT, Baraban SC. Large-scale phenotype-based antiepileptic drug screening in a Zebrafish model of Dravet syndrome(1,2,3). eNeuro 2015; 2: 1–19. - PMC - PubMed
    1. Griffin A, Hamling KR, Knupp K, Hong S, Lee LP, Baraban SC. Clemizole and modulators of serotonin signalling suppress seizures in Dravet syndrome. Brain 2017; 140: 669–83. - PMC - PubMed