[Effect of the mobile element jockey on the suppression of insertion mutations in the cut locus of Drosophila melanogaster]

Abstract

The data are reported on suppression of mutations at the cut locus induced by a mdg4 insertion carrying the other mobile element, "jockey". All mutations containing mdg4 with the jockey (ctMRpN) are suppressed by a classic suppressor su(Hw)2 and two new alleles obtained in this work. The extent of suppression increases, depending on the orientation of the jockey in mdg4 up to the point, when su(Hw) alleles known as recessive become semi-dominant. The jockey and mdg4 have been also found to influence the locus transcription in the norm and in case of suppression.