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Comment
. 2017 Jun;55(6):1608-1611.
doi: 10.1128/JCM.00430-17. Epub 2017 Apr 12.

The Immaculate Carbapenemase Study

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Comment

The Immaculate Carbapenemase Study

Kenneth S Thomson. J Clin Microbiol. 2017 Jun.

Abstract

Carbapenemase-producing organisms, or CPOs, are Gram-negative pathogens that produce a transmissible carbapenemase and are typically resistant to most (sometimes all) antibiotics. We now face a global CPO pandemic of high mortality. In this issue of the Journal of Clinical Microbiology, Karlowsky et al. (J Clin Microbiol 55:1638-1649, 2017, https://doi.org/10.1128/JCM.02316-16) report the results of an extensive global surveillance study that provide much-needed information that enhances our understanding of carbapenemase-producing Enterobacteriaceae (CPE) and which will be valuable for the development of improved strategies for CPE control and therapy of infections.

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References

    1. Carmeli Y, Akova M, Cornaglia G, Daikos GL, Garau J, Harbarth S, Rossolini GM, Souli M, Giamarellou H. 2010. Controlling the spread of carbapenemase-producing Gram-negatives: therapeutic approach and infection control. Clin Microbiol Infect 16:102–111. doi:10.1111/j.1469-0691.2009.03115.x. - DOI - PubMed
    1. Watanabe M, Iyobe S, Inoue M, Mitsuhashi S. 1991. Transferable imipenem resistance in Pseudomonas aeruginosa. Antimicrob Agents Chemother 35:147–151. doi:10.1128/AAC.35.1.147. - DOI - PMC - PubMed
    1. Walsh TR. 2010. Emerging carbapenemases: a global perspective. Int J Antimicrob Agents 36(Suppl 3):S8–S14. doi:10.1016/S0924-8579(10)70004-2. - DOI - PubMed
    1. Clinical and Laboratory Standards Institute. 2010. Performance standards for antimicrobial susceptibility testing; 20th informational supplement M100-S20. Clinical and Laboratory Standards Institute, Wayne, PA.
    1. de Araujo CF, Silva DM, Carneiro MT, Ribeiro S, Fontana-Maurell M, Alvarez P, Asensi MD, Zahner V, Carvalho-Assef AP. 2016. Detection of carbapenemase genes in aquatic environments in Rio de Janeiro, Brazil. Antimicrob Agents Chemother 60:4380–4383. doi:10.1128/AAC.02753-15. - DOI - PMC - PubMed

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