Vitamin C puts the pedal to the metal
- PMID: 28404860
- DOI: 10.1126/scitranslmed.aan2778
Vitamin C puts the pedal to the metal
Abstract
Increased iron in cancer cells drives selective sensitization of tumors to ascorbate treatment to prolong survival.
Copyright © 2017, American Association for the Advancement of Science.
Comment on
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O2⋅- and H2O2-Mediated Disruption of Fe Metabolism Causes the Differential Susceptibility of NSCLC and GBM Cancer Cells to Pharmacological Ascorbate.Cancer Cell. 2017 Apr 10;31(4):487-500.e8. doi: 10.1016/j.ccell.2017.02.018. Epub 2017 Mar 30. Cancer Cell. 2017. PMID: 28366679 Free PMC article. Clinical Trial.
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