Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2017 Apr;30(2):221-223.
doi: 10.1080/08998280.2017.11929594.

Bilateral respiratory epithelial adenomatoid hamartomas originating from the anterior olfactory clefts

Affiliations
Case Reports

Bilateral respiratory epithelial adenomatoid hamartomas originating from the anterior olfactory clefts

Jeffrey J Falco et al. Proc (Bayl Univ Med Cent). 2017 Apr.

Abstract

A respiratory epithelial adenomatoid hamartoma (REAH) is an uncommon benign lesion often found in the sinonasal tract. We present a case of bilateral REAH originating from the anterior olfactory cleft treated with endoscopic surgical resection without recurrence. We highlight the characteristics of REAH and necessary steps to ensure proper diagnosis and treatment.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
(a) Coronal and (b) sagittal T1 postcontrast MRI of the paranasal sinuses demonstrating bilateral enhancing polypoid lesions in the anterior olfactory cleft.
Figure 2.
Figure 2.
Hematoxylin and eosin–stained right nasal biopsy showing inflamed polypoid fragments of respiratory mucosa with features consistent with respiratory epithelial adenomatoid hamartoma. (a) 4× power, (b) 40× power.

References

    1. Al Hawat A, Mouchon E, De Bonnecaze G, Vergez S, Serrano E. Our experience with respiratory epithelial adenomatoid hamartomas of the olfactory cleft. Eur Arch Otorhinolaryngol. 2015;272(10):2867–2870. - PubMed
    1. Wenig BM, Heffner DK. Respiratory epithelial adenomatoid hamartomas of the sinonasal tract and nasopharynx: a clinicopathologic study of 31 cases. Ann Otol Rhinol Laryngol. 1995;104(8):639–645. - PubMed
    1. Nguyen DT, Gauchotte G, Arous F, Vignaud JM, Jankowski R. Respiratory epithelial adenomatoid hamartoma of the nose: an updated review. Am J Rhinol Allergy. 2014;28(5):187–192. - PubMed
    1. Wenig BM. World Health Organization Classification of Tumours. Pathology and Genetics: Head and Neck Tumours. Lyon, France: IARC Press, 2005, 33; Respiratory epithelial adenomatoid hamartoma. In Barnes L Eveson JW Reichart P Sidransky D eds.
    1. Albergotti WG, Psaltis AJ, Schlosser RJ. Respiratory epithelial adenomatoid hamartoma of the olfactory groove: a report of 4 cases and a review of the literature. Ear Nose Throat J. 2016;95(3):e19–e27. - PubMed

Publication types

LinkOut - more resources