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Comment
. 2017 Apr 12;21(4):415-416.
doi: 10.1016/j.chom.2017.03.014.

A RIPtide Protects Neurons from Infection

Ryan P Gilley  1 , William J Kaiser  2
Affiliations
Free article
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A RIPtide Protects Neurons from Infection

Ryan P Gilley et al. Cell Host Microbe. .
Free article

Abstract

RIPK3 and RIPK1 limit virus spread by executing either apoptotic or necroptotic cell death in response to infection. In a recent issue of Cell, Daniels et al. (2017) unveil an unexpected cell death-independent requirement of RIP kinase activity in coordinating neuroinflammation, restricting West Nile virus pathogenesis in neurons.

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