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. 2017 Sep;33(9):682-685.
doi: 10.1080/09513590.2017.1307960. Epub 2017 Apr 17.

The effect of oil and water-soluble contrast medium in hysterosalpingography on thyroid function

Shuhei So  1 , Wakasa Yamaguchi  1 , Hiroko Tajima  1 , Takeshi Nakayama  2 , Naoaki Tamura  3 , Naohiro Kanayama  3 , Fumiko Tawara  1
Affiliations
Free article

The effect of oil and water-soluble contrast medium in hysterosalpingography on thyroid function

Shuhei So et al. Gynecol Endocrinol. 2017 Sep.
Free article

Abstract

Hysterosalpingography (HSG) using iodinated contrast medium is X-ray diagnostic test that examines the inside of the uterus and fallopian tubes in infertile women. In this study, we compared thyroid function (thyroid stimulating hormone: TSH and free-T4: FT4 levels) after HSG with an oil-soluble contrast medium (OSCM) and a water-soluble contrast medium (WSCM). One hundred and sixty-four and 94 patients with normal thyroid function received HSG with OSCM and WSCM, respectively. Approximately 25% of the women in the OSCM group developed subclinical hypothyroidism (SCH), whereas only less than 10% of the patients in the WSCM group developed SCH. Our data clearly indicate that WSCM is safe for thyroid function in women who plan to get pregnant.

Keywords: Hysterosalpingography; infertility; oil-soluble contrast medium; subclinical hypothyroidism; water-soluble contrast medium.

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