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. 1988 Sep;62(9):3522-6.
doi: 10.1128/JVI.62.9.3522-3526.1988.

cis- and trans-acting regulation of gene expression of equine infectious anemia virus

P L Dorn  1 , D Derse
Affiliations

cis- and trans-acting regulation of gene expression of equine infectious anemia virus

P L Dorn et al. J Virol. 1988 Sep.

Abstract

Deletion analysis of the equine infectious anemia virus long terminal repeat revealed that sequences responsive to virus-specific transactivation are located within the region spanning the transcriptional start site (-31 to +22). In addition, an active exon of a trans-acting factor (tat) was identified downstream of pol and overlapping env (nucleotides 5264 to 5461). Activation by tat is accompanied by an increase in the steady-state levels of mRNA directed by the equine infectious anemia virus long terminal repeat.

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References

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    1. Nature. 1987 Apr 16-22;326(6114):711-3 - PubMed
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