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. 1988 Jun;8(6):2659-63.
doi: 10.1128/mcb.8.6.2659-2663.1988.

Absence of missense mutations in activated c-myc genes in avian leukosis virus-induced B-cell lymphomas

M Hahn  1 , W S Hayward
Affiliations

Absence of missense mutations in activated c-myc genes in avian leukosis virus-induced B-cell lymphomas

M Hahn et al. Mol Cell Biol. 1988 Jun.

Abstract

We have determined the nucleotide sequences of two independent DNA clones which contained the activated c-myc genes from avian leukosis virus-induced B-cell lymphomas. Neither of these c-myc genes contained missense mutations. This strongly supports the notion that the c-myc proto-oncogene in avian leukosis virus-induced B-cell lymphomas can be oncogenically activated by altered expression of the gene without a change in the primary structure of the gene product.

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References

    1. Cell. 1980 Nov;22(2 Pt 2):379-86 - PubMed
    1. Cell. 1988 Jan 29;52(2):185-95 - PubMed
    1. Nature. 1981 Apr 9;290(5806):475-80 - PubMed
    1. Nature. 1981 Aug 27;292(5826):857-8 - PubMed
    1. Nature. 1982 Jan 21;295(5846):209-14 - PubMed

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