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Comment
. 2016 Aug 5;4(1):13-14.
doi: 10.1080/23328940.2016.1208319. eCollection 2017.

Zika-related microcephaly in experimental models

Affiliations
Comment

Zika-related microcephaly in experimental models

Jean Pierre Schatzmann Peron et al. Temperature (Austin). .
No abstract available

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Figures

Figure 1.
Figure 1.
Maternal transfer of Zika to fetus in murine experimental model. Scheme illustrating the placental transference of Zika to fetus in SJL mice that are further born with the highlighted Zika-associated features. C57/Bl6 mice were shown resistant.

Comment on

  • The Brazilian Zika virus strain causes birth defects in experimental models.
    Cugola FR, Fernandes IR, Russo FB, Freitas BC, Dias JL, Guimarães KP, Benazzato C, Almeida N, Pignatari GC, Romero S, Polonio CM, Cunha I, Freitas CL, Brandão WN, Rossato C, Andrade DG, Faria Dde P, Garcez AT, Buchpigel CA, Braconi CT, Mendes E, Sall AA, Zanotto PM, Peron JP, Muotri AR, Beltrão-Braga PC. Cugola FR, et al. Nature. 2016 Jun 9;534(7606):267-71. doi: 10.1038/nature18296. Epub 2016 May 11. Nature. 2016. PMID: 27279226 Free PMC article.

References

    1. Li C, Xu D, Ye Q, Hong S, Jiang Y, Liu X, Zhang N, Shi L, Qin CF, Xu Z. Zika virus disrupts neural progenitor development and leads to microcephaly in mice. Cell Stem Cell 2016; 19:120–6; http://dx.doi.org/10.1016.j.stem.2016.04.017 - PubMed
    1. Cugola FR, Fernandes IR, Russo FB, Freitas BC, Dias JL, Guimarães KP, Benazzato C, Almeida N, Pignatari GC, Romero S, et al.. The Brazilian Zika virus strain causes birth defects in experimental models. Nature 2016; 534:267-71; PMID:27362221 - PMC - PubMed
    1. Miner JJ, Cao B, Govero J, Smith AM, Fernandez E, Cabrera OH, Garber C, Noll M, Klein RS, Noguchi KK, et al.. Zika virus infection during pregnancy in mice causes placental damage and fetal demise article zika virus infection during pregnancy in mice causes placental damage and fetal demise. Cell 2016; 165:1081-91; PMID:27180225; http://dx.doi.org/10.1016/j.cell.2016.05.008 - DOI - PMC - PubMed
    1. Higa LM, Trindade P, Delvecchio R, Tanuri A, Rehen SK. Zika virus impairs growth in human neurospheres and brain organoids 2016; 352:33-6 - PubMed
    1. Qian X, Nguyen HN, Song MM, Hadiono C, Ogden SC, Hammack C, Yao B, Hamersky GR, Jacob F, Zhong C, et al.. Brain-Region-Specific organoids using mini- bioreactors for modeling ZIKV exposure brain-region-specific organoids using mini-bioreactors for modeling ZIKV exposure. Cell 2016; 165:1238-54; PMID:27118425; http://dx.doi.org/10.1016/j.cell.2016.04.032 - DOI - PMC - PubMed

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