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Case Reports
. 1978;5(1):85-8.
doi: 10.1002/mpo.2950050113.

Accidental intrathecal administration of vincristine

D A Shepherd, C P Steuber, K A Starling, D J Fernbach
Case Reports

Accidental intrathecal administration of vincristine

D A Shepherd et al. Med Pediatr Oncol. 1978.

Abstract

Vincristine is a chemotherapeutic agent used in the treatment of various neoplastic diseases. Its neurotoxicity after therapeutic and pharmacologic doses has been well documented. We report a case of accidental intrathecal administration of vincristine in order to describe the complications seen, discuss possible means of therapeutic intervention, and serve as a reminder that preventive measures are mandatory to avoid such accidents in the future.

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