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Multicenter Study
. 2017 Jul 15;65(2):338-341.
doi: 10.1093/cid/cix318.

Adjunctive Corticosteroid Therapy in the Treatment of Coccidioidal Meningitis

George R Thompson 3rd  1   2 , Janis E Blair  3 , Sharon Wang  2 , Robert Bercovitch  4 , Michael Bolaris  5 , Dane Van Den Akker  6 , Rodrigo Lopez  7 , Arash Heidari  8 , Antonino Catanzaro  4 , Jose Cadena  7   9 , Peter Chin-Hong  10 , Brad Spellberg  11 , Royce Johnson  8
Affiliations
Multicenter Study

Adjunctive Corticosteroid Therapy in the Treatment of Coccidioidal Meningitis

George R Thompson 3rd et al. Clin Infect Dis. .

Abstract

Coccidioidal meningitis (CM) has high morbidity, and adjunctive measures to improve outcomes are needed. Using an established multicenter retrospective cohort study of CM (N = 221), we found that patients receiving adjunctive corticosteroids had a significant reduction in secondary cerebrovascular events (P = .0049). Those with CM-associated cerebrovascular events (8%) may benefit from short-term corticosteroids.

Keywords: coccidioidomycosis; corticosteroids; meningitis; stroke; vasculitis.

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References

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