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Comment
. 2017 Apr 18;46(4):522-524.
doi: 10.1016/j.immuni.2017.03.021.

Cell-Intrinsic Defense at the Epithelial Border Wall: Salmonella Pays the Price

Sky W Brubaker  1 , Denise M Monack  2
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Cell-Intrinsic Defense at the Epithelial Border Wall: Salmonella Pays the Price

Sky W Brubaker et al. Immunity. .
Free article

Abstract

Within the gut, Salmonella-infected enterocytes are expelled into the lumen, limiting pathogen replication. In this issue of Immunity, Rauch et al. (2017) expand our understanding of this cell-intrinsic response by characterizing the genetic determinants that control the expulsion and death of epithelial cells.

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