Pregabalin for the treatment of neuropathic pain: a narrative review for primary care providers

Abstract

Background: Neuropathic pain (NeP) is a distinct type of pain caused by damage to the nervous system itself. This often severe and chronic type of pain requires specific treatments that target the underlying pain pathophysiology.

Aim: The purpose of the current narrative review is to provide an overview of pregabalin (Lyrica ¹ ) for the treatment of NeP including its effects on pain, pain-related sleep interference, and other health-related outcomes, timing of therapeutic effect, safety and tolerability, and dosing. The information provided here will help primary care providers develop more effective NeP treatment strategies.

Keywords: Pregabalin; neuropathic pain; primary care; review.