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Review
. 2017 Apr 20;11(4):e0005454.
doi: 10.1371/journal.pntd.0005454. eCollection 2017 Apr.

Human African trypanosomiasis control: Achievements and challenges

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Review

Human African trypanosomiasis control: Achievements and challenges

Serap Aksoy et al. PLoS Negl Trop Dis. .

Abstract

Sleeping sickness, also known as human African trypanosomiasis (HAT), is a neglected disease that impacts 70 million people living in 1.55 million km2 in sub-Saharan Africa. Since the beginning of the 20th century, there have been multiple HAT epidemics in sub-Saharan Africa, with the most recent epidemic in the 1990s resulting in about half a million HAT cases reported between 1990 and 2015. Here we review the status of HAT disease at the current time and the toolbox available for its control. We also highlight future opportunities under development towards novel or improved interventions.

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Conflict of interest statement

The authors have declared that no competing interests exist.

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References

    1. Simarro P.P., Cecchi G., Franco J.R., Paone M., Diarra A., Ruiz-Postigo J.A., Fevre E.M., Mattioli R.C., and Jannin J.G. (2012). Estimating and mapping the population at risk of sleeping sickness. PLoS Negl Trop Dis 6, e1859 10.1371/journal.pntd.0001859 - DOI - PMC - PubMed
    1. Barrett M.P. (1999). The fall and rise of sleeping sickness. Lancet 353, 1113–1114. 10.1016/S0140-6736(98)00416-4 - DOI - PubMed
    1. Headrick D.R. (2014). Sleeping sickness epidemics and colonial responses in East and Central Africa, 1900–1940. PLoS Negl Trop Dis 8, e2772 10.1371/journal.pntd.0002772 - DOI - PMC - PubMed
    1. Alsan M. (2015). The Effect of the TseTse Fly on African Development. American Economic Review 382–410.
    1. Franco J.R., Simarro P.P., Diarra A., Ruiz-Postigo J.A., and Jannin J.G. (2014). The journey towards elimination of gambiense human African trypanosomiasis: not far, nor easy. Parasitology 141, 748–760. 10.1017/S0031182013002102 - DOI - PubMed

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