Stem cells: Two sides to cancer stem cells in colorectal cancer

Comment

Katrina Ray. Nat Rev Gastroenterol Hepatol. 2017 Jun.

. 2017 Jun;14(6):325.

doi: 10.1038/nrgastro.2017.52. Epub 2017 Apr 21.

No abstract available

Comment on

A distinct role for Lgr5⁺ stem cells in primary and metastatic colon cancer.
de Sousa e Melo F, Kurtova AV, Harnoss JM, Kljavin N, Hoeck JD, Hung J, Anderson JE, Storm EE, Modrusan Z, Koeppen H, Dijkgraaf GJ, Piskol R, de Sauvage FJ. de Sousa e Melo F, et al. Nature. 2017 Mar 29;543(7647):676-680. doi: 10.1038/nature21713. Nature. 2017. PMID: 28358093

Non-Stem Cells Seed Colorectal Cancer Metastases and Gain Stem Traits.
[No authors listed] [No authors listed] Cancer Discov. 2020 May;10(5):OF9. doi: 10.1158/2159-8290.CD-RW2020-042. Epub 2020 Mar 20. Cancer Discov. 2020. PMID: 32198132
The G-protein coupled receptor 56, expressed in colonic stem and cancer cells, binds progastrin to promote proliferation and carcinogenesis.
Jin G, Sakitani K, Wang H, Jin Y, Dubeykovskiy A, Worthley DL, Tailor Y, Wang TC. Jin G, et al. Oncotarget. 2017 Jun 20;8(25):40606-40619. doi: 10.18632/oncotarget.16506. Oncotarget. 2017. PMID: 28380450 Free PMC article.
Colorectal cancer stem cells: from the crypt to the clinic.
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Targeting the Colorectal Cancer Stem Cell.
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