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Review
. 2017 Apr 17:5:11.
doi: 10.1186/s41038-017-0076-x. eCollection 2017.

Nutrition and metabolism in burn patients

Audra Clark  1 , Jonathan Imran  1 , Tarik Madni  1 , Steven E Wolf  1
Affiliations
Review

Nutrition and metabolism in burn patients

Audra Clark et al. Burns Trauma. .

Abstract

Severe burn causes significant metabolic derangements that make nutritional support uniquely important and challenging for burned patients. Burn injury causes a persistent and prolonged hypermetabolic state and increased catabolism that results in increased muscle wasting and cachexia. Metabolic rates of burn patients can surpass twice normal, and failure to fulfill these energy requirements causes impaired wound healing, organ dysfunction, and susceptibility to infection. Adequate assessment and provision of nutritional needs is imperative to care for these patients. There is no consensus regarding the optimal timing, route, amount, and composition of nutritional support for burn patients, but most clinicians advocate for early enteral nutrition with high-carbohydrate formulas. Nutritional support must be individualized, monitored, and adjusted throughout recovery. Further investigation is needed regarding optimal nutritional support and accurate nutritional endpoints and goals.

Keywords: Burn; Critical care; Metabolism; Nutrition.

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Figures

Fig. 1
Fig. 1
Hypermetabolic response after severe burn, trauma, and sepsis. Adapted from references [5, 6, 123, 124]
Fig. 2
Fig. 2
Metabolism of protein, carbohydrates, and lipids
See this image and copyright information in PMC

References

    1. Dickerson RN, Gervasio JM, Riley ML, Murrell JE, Hickerson WL, Kudsk KA, et al. Accuracy of predictive methods to estimate resting energy expenditure of thermally-injured patients. J Parenter Enteral Nutr. 2002;26(1):17–29. doi: 10.1177/014860710202600117. - DOI - PubMed
    1. Rousseau A-F, Losser M-R, Ichai C, Berger MM. ESPEN endorsed recommendations: nutritional therapy in major burns. Clin Nutr. 2013;32(4):497–502. doi: 10.1016/j.clnu.2013.02.012. - DOI - PubMed
    1. Suri MP, Dhingra VJS, Raibagkar SC, Mehta DR. Nutrition in burns: need for an aggressive dynamic approach. Burns. 2006;32(7):880–884. doi: 10.1016/j.burns.2006.02.006. - DOI - PubMed
    1. Cuthbertson DP, Angeles Valero Zanuy MA, Leon Sanz ML. Post-shock metabolic response. 1942. Nutr Hosp. 2001;16(5):176-182; discussion 175-176. - PubMed
    1. Porter C, Tompkins RG, Finnerty CC, Sidossis LS, Suman OE, Herndon DN. The metabolic stress response to burn trauma: current understanding and therapies. Lancet. 2016;388(10052):1417–1426. doi: 10.1016/S0140-6736(16)31469-6. - DOI - PMC - PubMed