Building a Translational Microbiome Toolbox
- PMID: 28431240
- DOI: 10.1016/j.cell.2017.04.009
Building a Translational Microbiome Toolbox
Abstract
Designing successful microbiota-based therapies requires in-depth understanding of the ecological foundations of this community. In this issue, two studies by Whitaker et al. and Lim et al. provide refined genetic tools for dissecting the spatial organization and temporal dynamics of bacterial communities at the single-cell and -gene levels.
Published by Elsevier Inc.
Comment on
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Tunable Expression Tools Enable Single-Cell Strain Distinction in the Gut Microbiome.Cell. 2017 Apr 20;169(3):538-546.e12. doi: 10.1016/j.cell.2017.03.041. Cell. 2017. PMID: 28431251 Free PMC article.
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Engineered Regulatory Systems Modulate Gene Expression of Human Commensals in the Gut.Cell. 2017 Apr 20;169(3):547-558.e15. doi: 10.1016/j.cell.2017.03.045. Cell. 2017. PMID: 28431252 Free PMC article.
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