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. 1988 Aug 30;155(1):524-9.
doi: 10.1016/s0006-291x(88)81118-5.

Structure of a novel human granulocyte peptide with anti-ACTH activity

A Singh  1 , A Bateman, Q Z Zhu, S Shimasaki, F Esch, S Solomon
Affiliations

Structure of a novel human granulocyte peptide with anti-ACTH activity

A Singh et al. Biochem Biophys Res Commun. .

Abstract

We report the purification, structure and biological properties of a peptide of novel sequence from human granulocytes that inhibits ACTH stimulated synthesis of corticosterone in rat adrenal cell suspensions. The peptide HP-4 is homologous to a previously described human granulocyte peptide HP-1 that has no anti-ACTH activity.

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