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Case Reports
. 2017 Apr 22:2017:bcr2017219806.
doi: 10.1136/bcr-2017-219806.

Lingual hyperpigmentation after 5-fluorouracil chemotherapy

Michael Lawrenz Co  1 , Marcus Juan Esteban  1
Affiliations
Case Reports

Lingual hyperpigmentation after 5-fluorouracil chemotherapy

Michael Lawrenz Co et al. BMJ Case Rep. .
No abstract available

Keywords: Cancer intervention; Chemotherapy; Dermatology; Gastrointestinal system; Unwanted effects / adverse reactions.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Hyperpigmented papules and plaques on the tongue 3 days after chemotherapy.
Figure 2
Figure 2
Almost complete spontaneous resolution of hyperpigmentation 4 weeks after chemotherapy.
See this image and copyright information in PMC

References

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    1. Alfreijat M. Tongue hyperpigmentation associated with chemotherapy. J Community Hosp Intern Med Perspect 2013;3:21047.10.3402/jchimp.v3i3-4.21047 - DOI - PMC - PubMed
    1. Sreeja C, Ramakrishnan K, Vijayalakshmi D, et al. . Oral pigmentation: a review. J Pharm Bioallied Sci 2015;7:403–8.10.4103/0975-7406.163471 - DOI - PMC - PubMed
    1. Marcelo B, Nakhle S. Chemotherapy-induced hyperpigmentation of the tongue. N Engl J Med 2011;365:e20.10.1056/NEJMicm1014268 - DOI - PubMed
    1. Petrelli F, Cabiddu M, Barni S. 5-Fluorouracil or capecitabine in the treatment of advanced colorectal cancer: a pooled-analysis of randomized trials. Med Oncol 2012;29:1020–9.10.1007/s12032-011-9958-0 - DOI - PubMed

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