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. 1988 Sep;80(1):31-8.
doi: 10.1007/BF00451451.

Nephrogenic diabetes insipidus: close linkage with markers from the distal long arm of the human X chromosome

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Nephrogenic diabetes insipidus: close linkage with markers from the distal long arm of the human X chromosome

N Knoers et al. Hum Genet. 1988 Sep.

Abstract

Ten families with nephrogenic diabetes insipidus (NDI) have been analysed for restriction fragment length polymorphisms (RFLPs). A search for linkage was performed using various chromosome-specific single-copy DNA probes of known regional assignment to the human X chromosome. Close linkage was found between the disease locus and the markers DXS52, DXS15, DXS134 and the F8 gene. This result assigns the NDI gene to the subtelomeric region of the long arm of the X chromosome. The regional localization of the gene by the identification of closely linked markers should have repercussions for genetic counselling and prevention in NDI families.

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References

    1. Cytogenet Cell Genet. 1987;46(1-4):277-315 - PubMed
    1. AMA J Dis Child. 1960 Feb;99:164-74 - PubMed
    1. Lancet. 1956 Nov 24;271(6952):1069-73 - PubMed
    1. Science. 1986 Apr 4;232(4746):65-8 - PubMed
    1. Ann Neurol. 1987 Apr;21(4):349-52 - PubMed

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