Genetic translocation in Staphylococcus aureus
- PMID: 284355
- PMCID: PMC382947
- DOI: 10.1073/pnas.76.1.400
Genetic translocation in Staphylococcus aureus
Abstract
A 5.2-kilobase pair transposon, Tn551, has been found in Staphylococcus aureus, a Gram-positive bacterium. Initially detected on plasmid pI258, it undergoes rec-independent transposition to multiple chromosomal and plasmid sites, sometimes causing insertional inactivation. Unlike most other transposons, Tn551 undergoes apparently precise excision as a rule. The initial observation of Tn551 transition involved UV inactivation of the carrier plasmid; this would appear to be a general means of detecting transposable elements.
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