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Review
. 2017;88(1):6-14.
doi: 10.1159/000471876. Epub 2017 Apr 24.

The Physiology of Childhood Growth: Hormonal Regulation

Emelie Benyi, Lars Sävendahl
Review

The Physiology of Childhood Growth: Hormonal Regulation

Emelie Benyi et al. Horm Res Paediatr. 2017.

Abstract

The growth patterns of a child changes from uterine life until the end of puberty. Height velocity is highest in utero and declines after birth until puberty when it rises again. Important hormonal regulators of childhood growth are growth hormone, insulin-like growth factor 1, sex steroids, and thyroid hormone. This review gives an overview of these hormonal regulators of growth and their interplay with nutrition and other key players such as inflammatory cytokines.

Keywords: Growth; Growth and puberty; Growth factor; Growth hormone; Growth hormone physiology; Growth in children; Hormones; Normal growth/auxology; Nutrition.

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