Critical Need for Clarity in Polymyxin B Dosing
- PMID: 28438796
- PMCID: PMC5404569
- DOI: 10.1128/AAC.00208-17
Critical Need for Clarity in Polymyxin B Dosing
Keywords: pharmacodynamics; pharmacokinetics; polymyxin B.
Comment on
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Dosing and Pharmacokinetics of Polymyxin B in Patients with Renal Insufficiency.Antimicrob Agents Chemother. 2016 Dec 27;61(1):e01337-16. doi: 10.1128/AAC.01337-16. Print 2017 Jan. Antimicrob Agents Chemother. 2016. PMID: 27799209 Free PMC article.
References
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- Sandri AM, Landersdorfer CB, Jacob J, Boniatti MM, Dalarose MG, Falci DR, Behle TF, Bordinhao RC, Wang J, Forrest A, Nation RL, Li J, Zavascki AP. 2013. Population pharmacokinetics of intravenous polymyxin B in critically Ill patients: implications for selection of dosage regimens. Clin Infect Dis 57:524–531. doi:10.1093/cid/cit334. - DOI - PubMed
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- Bedford Laboratories. 2011. Polymyxin B for injection. USP package insert. Bedford Laboratories, Bedford, OH.
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- Nelson BC, Eiras DP, Gomez-Simmonds A, Loo AS, Satlin MJ, Jenkins SG, Whittier S, Calfee DP, Furuya Y, Kubin CJ. 2015. Clinical outcomes associated with polymyxin B dose in patients with bloodstream infections due to carbapenem-resistant Gram-negative rods. Antimicrob Agents Chemother 59:7000–7006. doi:10.1128/AAC.00844-15. - DOI - PMC - PubMed
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