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. 2017 Apr 24;41(2):125-126.
doi: 10.1016/j.devcel.2017.04.005.

It's T Time for Normal Blood Vessels

Bernard Thienpont  1 , Diether Lambrechts  2
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It's T Time for Normal Blood Vessels

Bernard Thienpont et al. Dev Cell. .
Free article

Abstract

In a new report in Nature, Tian and colleagues (2017) describe that T cell activation in tumors induces blood vessel normalization. Because abnormal vasculature in tumors is known to reduce chemotherapy effectiveness and T lymphocyte infiltration and to increase metastasis, this suggests an exciting novel angle for checkpoint immunotherapy.

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