Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Apr;35(2):79-83.
doi: 10.2337/cd16-0018.

Patients With Diabetes and Chronic Liver Disease Are at Increased Risk for Overall Mortality: A Population Study From the United States

Maria Stepanova  1   2 , Stephen Clement  3 , Robert Wong  4 , Sammy Saab  5 , Aijaz Ahmed  6   7 , Zobair M Younossi  1   2   8
Affiliations

Patients With Diabetes and Chronic Liver Disease Are at Increased Risk for Overall Mortality: A Population Study From the United States

Maria Stepanova et al. Clin Diabetes. 2017 Apr.

Abstract

IN BRIEF Chronic liver disease (CLD) and type 2 diabetes have both been linked to increased morbidity and mortality. In this study, the impact of CLD and diabetes on all-cause mortality was quantified at the population level using U.S. population data. Both type 2 diabetes and CLD were found to be independently associated with increased mortality (age-adjusted hazard ratio [aHR] 1.98 and 1.37 for diabetes and CLD, respectively), and having both diabetes and CLD substantially increased the risk of mortality (aHR 2.41).

PubMed Disclaimer

Figures

FIGURE 1.
FIGURE 1.
Age-adjusted mortality in the U.S. population with and without CLD and/or type 2 diabetes. Zero time point represents screening for NHANES. P values are reported at 4, 8, 12, and 16 years of follow-up, respectively (P& between CLD and no CLD in subjects without diabetes; Pα between CLD and no CLD in those with diabetes; Pβ between diabetes and no diabetes in subjects without CLD; Pγ between diabetes and no diabetes in those with CLD).
See this image and copyright information in PMC

References

    1. Centers for Disease Control and Prevention Chronic diseases: the leading causes of death and disability in the United States [Internet]. Available from http://www.cdc.gov/chronicdisease/overview. Accessed 20 June 2016
    1. Schiller JS, Lucas JW, Ward BW, Peregoy JA. Summary health statistics for US adults: National Health Interview Survey, 2010. Vital Health Stat 10 2012;252:1–207 - PubMed
    1. Centers for Disease Control and Prevention/National Center for Health Statistics Health Interview Survey, 1997–2014: sample adult core component. Early release of selected estimates based on data from the National Health Interview Survey, 2014: diagnosed diabetes [Internet]. Available from http://www.cdc.gov/nchs/data/nhis/earlyrelease/earlyrelease201506_14.pdf. Accessed 20 June 2016
    1. Centers for Disease Control and Prevention/National Center for Health Statistics Health Interview Survey, 1997–2014: sample adult core component. Early release of selected estimates based on data from the National Health Interview Survey, 2014: diagnosed obesity [Internet]. Available from http://www.cdc.gov/nchs/data/nhis/earlyrelease/earlyrelease201506_06.pdf. Accessed 20 June 2016
    1. Flegal KM, Carroll MD, Kit BK, Ogden CL. Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999–2010. JAMA 2012;307:491–497 - PubMed