Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Apr;79(2):169-172.
doi: 10.1007/s12262-016-1502-1. Epub 2016 May 16.

Dermatofibrosarcoma Protuberance of the Breast: a Diagnostic Challenge

Ismail A S Burud  1 , Ng Sze How  2 , Gan CheeWei  3 , Suboh Roslina  4
Affiliations

Dermatofibrosarcoma Protuberance of the Breast: a Diagnostic Challenge

Ismail A S Burud et al. Indian J Surg. 2017 Apr.

Abstract

Dermatofibrosarcoma protuberans (DFSP) is an uncommon slow growing neoplasm of the dermis with tendency to invade the subcutaneous tissues. It presents during the third to fourth decade of life and is commonly seen over the trunk, extremities and head and neck. DFSP presenting as a breast lump is rare but few cases have been reported in the literature. Pre-operative diagnosis with mammography, ultrasonography and FNAC is challenging. We report a case of a DFSP of the right breast in a middle aged lady with history of recurrent breast lumps excised and diagnosed in the past as benign. She presented with progressively increasing right breast lump of 2 months duration. She underwent wide local excision and histology revealed dermatofibrosarcoma protuberans. In view of its local aggressiveness with incomplete surgical margin, mastectomy was performed.

Keywords: Breast; Dermatofibrosarcoma protuberans; Immunohistochemical stains; Mastectomy.

PubMed Disclaimer

Conflict of interest statement

There is no conflict of interest or any financial support involved in this case report. It has not been published or presented in printed or electronic form.

Figures

Fig. 1
Fig. 1
Mammogram showing BIRADS 3 lesion
Fig. 2
Fig. 2
Ultrasonography of the right breast showing lesion at 10 o’clock
Fig. 3
Fig. 3
H and E ×10: part of tumour with infiltrative margin into subcutaneous tissue
Fig. 4
Fig. 4
H and E ×10: tumour cells arranged in storiform pattern
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Yeniay L, Unlap O, Sezak M, Yilmaz R. Dermatofibrosarcoma protuberans of the breast. Breast J. 2012;18(5):493–494. doi: 10.1111/j.1524-4741.2012.01282.x. - DOI - PubMed
    1. Bogucki B, Neuhaus I, Hurst E. Dermatofibrosarcoma protuberance: a review of literature. Dermatol Surg. 2012;38:537–551. doi: 10.1111/j.1524-4725.2011.02292.x. - DOI - PubMed
    1. Nggada H, Bali B, Na’aya H. A clinicopathological study of dermatofibrosarcoma protuberans in Maiduguri, northeastern Nigeria. Niger J Surg Res. 2006;8(1–2):78–80.
    1. Liu S, Ho T, Hsu S, Zhan H, Chou C. Imaging of dermatofibrosarcoma protuberans of breast. Breast J. 2010;16(5):541–543. doi: 10.1111/j.1524-4741.2010.00955.x. - DOI - PubMed
    1. Ivanovic D, Prvulovic N, Stojanovic D, Sveljo O, Vicko F, Kapiel T. Dermatofibrosarcoma protuberance of the breast: mammographic, ultrasound, MRI and MRS features. Arch Gynecol Obstet. 2009;280:827–830. doi: 10.1007/s00404-009-1004-5. - DOI - PubMed

LinkOut - more resources